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Symbol
Name
ID
Pole
polymerase (DNA directed), epsilon
MGI:1196391
Phenotype annotations related to digestive/alimentary system
Darker colors indicate more annotations
Human Phenotypes
Adenocarcinoma of the colon
Hereditary nonpolyposis colorectal carcinoma
Adenomatous colonic polyposis
Neoplasm of the stomach
Adenocarcinoma of the small intestine
Disease(s) Associated with POLE
colorectal cancer
mismatch repair cancer syndrome

Mouse Phenotypes
increased intestinal adenocarcinoma incidence
increased colon adenocarcinoma incidence
increased small intestine adenocarcinoma incidence
increased intestinal adenoma incidence
Availability Mouse Genotype
Poletm1.1Bdp/Poletm1.1Bdp

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory